Oscar Ray Grimes Sr. (September 11, 1893 – May 25, 1953) was a first baseman in Major League Baseball who played for the Boston Red Sox (1920), Chicago Cubs (1921–1924) and Philadelphia Phillies (1926).

He appeared in a game with the Boston Red Sox in 1920 before being traded to the Cubs in 1921.

In 1922, while with the Cubs, Grimes set a major-league mark with at least one RBI over 17 consecutive games (from June 27 to July 23), a record which still stands.

As noted by baseball historian Clifton Blue Parker, "It is a little-known record, but perhaps one of the most enduring and challenging ones.

In a six-season career, Grimes was a .329 hitter with 27 home runs and 263 RBI in 433 games.