[1] In the game, the player assumes the role of a fighter pilot from Earth controlling the RT-X-32 space craft to fight against the biomechanical Zoul Empire.

[2][3] The player controls the ship through eight increasingly difficult stages over a constantly scrolling background, populated with an assortment of bioships, organic fortresses and obstacles.

[2] Getting hit by enemy fire or colliding against solid stage obstacles will result in losing a life, as well as a penalty of decreasing the ship's firepower and loss of the weapon that was currently in use, and the game is over once all lives are lost, though the player has unlimited continues to keep playing.

[3] Rayxanber was developed by Team 50, a group within Data West composed of director Kazuhide Nakamura, programmer Takayasu Sato, artists Takeharu Igarashi and Yoshiko Miyamoto, producer Naokazu Akita and two playtesters.

[1][3][4][7] In a 2020 interview with Japanese gaming website DenFaminicoGamer, a Data West representative commented that there were no current plans for a digital re-release of the Rayxanber series through their official online store, but would consider it if there is demand.

[1] The Japanese publication Micom BASIC Magazine ranked the game at the number thirty-one spot in popularity on their July 1990 issue.