[1] A non-proprietary alternative for RDT is IETF's Real-time Transport Protocol (RTP), which is also implemented in RealNetworks players.
[1] As reported in a 2002 book about firewalls, RDT used two unidirectional UDP connections, one for the data sent from the server to the client and another in the opposite direction for retransmission requests.
The same book reported that RealNetworks' G2 server used RDT in this configuration by default.
[2] Another 2003 book reported that RDT was also seen carried over Transmission Control Protocol (TCP), as a fall-back mechanism.
[1] RDT is now included as part of the Helix Community project.