It has been crossed with Jerseys in many places, including India, the United States, Australia, Sri Lanka, etc.

They are distinguished from the other dairy breed of Sindh, the Tharparkar or White Sindhi, both by colour and form, the Red Sindhi is smaller, rounder, with a more typical dairy form, and with short, curved horns, while the Tharparkar are taller with a shape more typical of Zebu draft breeds, and with longer, lyre shaped horns.

It has also been used to improve beef and dual purpose cattle in many tropical countries, as it is sufficiently meaty to produce good beef calves in such crosses and the high milk production helps give a fast-growing calf which is ready for market at one year.

This has caused it to lose favour with some commercial dairies in India and Pakistan, which have been phasing out their Red Sindhi herds by breeding to Sahiwal bulls for a few generations.

Red Sindhi cattle are also used for milk production in Brazil, but this race of zebu is not popular as others.