There were no passengers on board, but 5 of the 8 crew members were killed when the aircraft hit a ditch and highway structures after overrunning the runway.

A Moscow Vnukovo to Novosibirsk flight on 20 December 2012 (operated by a Tupolev Tu-204 registered as RA-64049) overran runway 25 at Tolmachevo Airport by 350 metres (1,150 ft) when its brakes failed on landing.

As a result of that incident, on 24 December the Federal Air Transport Agency of Russia (Rosaviatsia) issued a mandatory Airworthiness Directive requiring Red Wings and all other operators of the Tu-204 to inspect and apply extra lubrication to the braking system drive mechanism limit switches, located on the main landing shock absorber, "before next departure".

[4][5] On 30 December Rosaviatsia chief Alexander Neradko announced that a preliminary examination of the aircraft's flight data recorder indicated that the flight had touched down in the proper landing area but, as in the 20 December incident in Novosibirsk, the braking system on RA-64047 appeared to have failed in the fatal Moscow overrun accident as well.

The approach was performed without significant deviations from the glide path, and the aircraft passed over the start of the runway at a height of 15 metres (49 ft) and an airspeed of 260 kilometres per hour (140 kn; 160 mph).

Five seconds after the throttle had been retarded to idle, the aircraft touched down, between 900 and 1,000 metres (2,953 and 3,281 ft) along the runway, at a speed of 230 kilometres per hour (120 kn; 140 mph).

Almost simultaneously with the touchdown of the nose landing gear, the crew put the engines into reverse thrust and applied the mechanical brakes.

[11] As a safety feature, both sets of main landing gear were required to be compressed simultaneously before the thrust reversers could deploy.

One of the flight attendants was ejected from the aircraft and landed on an adjacent road; she was confirmed to be dead in an ambulance transporting her to the hospital.