Most part of this schedule was occupied by Japanese cartoons and American series like Sex and the City, The X-Files and That '70s Show.

With a UHF signal concession obtained by the Bandeirantes Communication Group in 1989,[1] Rede 21 went on air on October 21, 1996, initially broadcasting only to Greater São Paulo.

[2] The network had presence in 14 cities in 2004, but in this time of the year lost affiliates in Porto Alegre, Belo Horizonte, Vitória and Rio de Janeiro.

The newscast host and the Blog 21 hosts were fired and was canceled the programs Top of the Pops, Doc 21 (with the National Geographic documentaries), the sitcom Seinfeld and Top of the Pops Brasil and put on air the Gamecorp programs.

After two years off the air, on July 7, 2008, Rede 21 came back on, after the disaccord between Grupo Bandeirantes and Gamecorp.