In June 2000, the Texas Parks and Wildlife Department designated the bay as a scientific area to study the seagrass, as a result, the Redfish Bay State Scientific Area was established.

[3] Every February since 2007, the city of Aransas Pass holds the Redfish Bay Trash Parade and Coastal Cleanup, an event that encourages the removal of trash and waste from the bay, due to pollution.

[4] In 2009, 90 volunteers cleared three pickup loads of trash that included syringes, construction hard hats, ribbons and busted balloons.

A fish-killing microorganism was found in Corpus Christi Bay that was believed to be responsible.

In December 1983, three people were injured and between $2 and $3 million of damage was done to the Corpus Christi Oil Refining Corporation's Redfish Bay Terminal near the bay in Aransas Pass, following an explosion of five oil tanks.