[11] An alternative theory explains the male refractory period in terms of a peripheral autonomic feedback mechanism,[citation needed] rather than through central chemicals like oxytocin, serotonin, and prolactin.
This theory suggests that after ejaculation, decreased wall tension in structures such as the seminal vesicles leads to a change in the fine autonomic signals sent from these organs, effectively creating a negative feedback loop.
[3][4] A study has shown that the vast majority of women experience clitoral hypersensitivity after orgasm at similar rates to the refractory period in men, which is characterised by penile sensitivity.
The findings of that same study also suggest a reconsideration of the refractory period in women and highlight the need for further research on post-orgasmic experiences that includes the female perspective.
[13] In addition, both men and women experience increased prolactin levels following orgasm for approximately 60 minutes, which is a neurobiological marker of the refractory period in males.