Reginald "Reg" Jirod Jefferson (born September 25, 1968) is a former designated hitter who played for from 1991 to 1999 the Cincinnati Reds, Cleveland Indians, Seattle Mariners and the Boston Red Sox.

Reggie attended Lincoln High School in Tallahassee; he was a three-sport star, lettering in baseball, basketball and football.

He was traded in the winter of 1993 by Cleveland to Seattle with Félix Fermín and cash for shortstop Omar Vizquel.

Unable to hit left-handed pitchers, he was left off the 1999 playoff roster as a result.

[2] In 680 games over nine seasons, Jefferson posted a .300 batting average (637-for-2123) with 285 runs, 131 doubles, 11 triples, 72 home runs, 300 RBI, 146 bases on balls, .349 on-base percentage and .474 slugging percentage.