[5] As a senior, he started all 12 games at left guard for the 1971 Michigan team that compiled an 11-1 record, scored 421 points,[6] and broke Michigan's all-time record with 3,977 net rushing yards (331 rushing yards per game).

[1] He and Joe DeLamielleure were O. J. Simpson's pulling guards on his frequent sweep runs that made him the first 2,000-yard rusher during the 1973 NFL season.

[8][9] He was often referred to by Simpson as his "main man" and was the leader of the team's "Electric Company" which "turned on the Juice".

He is also the founder of the Reggie McKenzie Foundation, an organization that helps Detroit youth with athletics and academics.

He played eight seasons in the NFL, winning Super Bowl XXXI with Green Bay.