Régine Alexandra Chassagne (French pronunciation: [ʁeʒin ʃasaɲ]; born 19 August 1976)[1] is a Canadian singer, songwriter, musician, and multi-instrumentalist, and is a member of the band Arcade Fire.

[8][9] Chassagne has also been involved with a medieval-themed band called Les Jongleurs de la Mandragore[10] and with Jimmy Rouleau in the jazz duo Azúcar.

She plays many instruments on stage, including accordion, drums, xylophone, hurdy-gurdy, keyboards, organ and guitar.

In Arcade Fire, Chassagne performs lead vocals on some songs, including "Haiti", "In the Backseat", "Black Wave/Bad Vibrations", "Empty Room", "Abraham's Daughter", "Sprawl II (Mountains Beyond Mountains)", "Creature Comfort", "Electric Blue", and "Unconditional II (Race and Religion)".

In March 2015, Chassagne, along with Win Butler, attended the launch of music streaming service Tidal, and revealed themselves, along with other notable artists, as shareholders in the company.