Trang, Ranong, Phang Nga, Chumphon and Hat Yai were newly formed sides and Surat Thani were welcomed into the setup after being relegated from the 1st Division.

Prachuap Khiri Khan were also re-located from the Regional League Central-East Division by the RL board but withdrew before the 1st round of games citing insufficient budget and concerns about safety.

Phuket, who struggled in their first season in 2009 won the title, leading the league from start to finish.

They had formed close links in the off season with TPL side Muangthong United and brought in a number of loanee players.

A disastrous campaign in Division 1 saw them on the brink of financial collapse and they reformed as Nara United for the 2011 season.