Originally known as the AmSouth-Harbert Plaza, it was renamed on July 13, 2007, after AmSouth Bancorporation - the building's largest tenant - merged with Birmingham-based Regions Financial Corporation.

Today, the 200,000 square feet (19,000 m2) that Regions leases makes it the building's largest tenant.

Designed by the architectural firm Hellmuth, Obata & Kassabaum, the Plaza was built in 1989 by general contractor Brasfield & Gorrie as a multi-tenant office building for Harbert Corporation.

The building also connects to the adjacent Regions Center through the mezzanine level.

Major tenants include Regions Financial Corporation; law firms Balch & Bingham, Waller Lansden Dortch & Davis, LLP and Maynard Cooper & Gale; an IT Professional Services Firm Insight Global, the accounting firm Ernst & Young and Northwestern Mutual, and a custom clothier, John Armstrong Clothier.