Reliance is a town in Lyman County, South Dakota, United States.

It rises about 200 feet above the prairie, and is sacred to the Brulé Sioux people, especially those who live on the nearby Lower Brule Indian Reservation.

26.0% of all households were made up of individuals, and 12.3% had someone living alone who was 65 years of age or older.

The racial makeup of the town was 90.29% White, 5.34% Native American, and 4.37% from two or more races.

32.1% of all households were made up of individuals, and 11.9% had someone living alone who was 65 years of age or older.

About 4.1% of families and 11.2% of the population were below the poverty line, including 9.2% of those under the age of eighteen and 24.0% of those 65 or over.