In his childhood, he began studying the five key wooden flute with the renowned flutist Antonio Arcaño,[1][3] and at the age of fourteen he was already performing live with orchestras in the city.
Around the same time he substituted in some performances for flutist Miguel O'Farrill during the season of the Enrique Jorrín Orchestra's show Cabaret at the Hotel Capri.
Two years later he recorded the album René Lorente y su charanga cubana, and in 1995 he decided to start a career as a solo instrumentalist exploring other genres like Latin jazz, pop, rock and African rhythms.
During that period he also collaborated as a guest artist with various charangas, and at the end of the 1990s he joined the group Café Nostalgia in the city of Miami, with which he recorded the albums Live (1997) and Te di la vida entera (1999).
[1][7] Throughout his career, Lorente has recorded or performed with artists and groups like Hansel Martínez, Fred Paul, Albita Rodríguez, Meme Solís, Juanito Márquez, Juan Pablo Torres, Cachao López, Haitiando, Roberto Torres, Chucho Valdés, Alfredo Armenteros, César Pedroso, Grupo Canela and Su Majestad el Danzón,[1][8][9] and has appeared on television programs on networks such as Telemundo, América TeVe, Univision and MegaTV.