René Manuel Santiago García (born April 10, 1992) is a Puerto Rican professional boxer who has held the World Boxing Organization (WBO) interim light flyweight title since October 2023.
Santiago turned professional in 2014 and compiled a record 12–3 before facing & defeating Nicaraguan Kevin Vivas, to win the vacant WBO light flyweight interim title.
[1][2] Santiago challenged Jonathan Gonzalez for WBO light flyweight title in San Juan, Puerto Rico on March 2, 2024.
He lost the fight by unanimous decision.
[3][4] Santiago is scheduled to face Azael Villar in a 10-round light flyweight bout in Humacao, Puerto Rico on October 30, 2024.