René Wilke (born 30 June 1984) is a German politician (Die Linke), Lord Mayor of Frankfurt (Oder), and a former member of Brandenburg's regional parliament.

Wilke remained in this position for 12 years and hence steered the transition from PDS to DIE LINKE in Frankfurt before he decided not to seek re-election for this office in 2014.

Wilke worked amongst others, for the Rosa Luxemburg Foundation (German: Rosa-Luxemburg Stiftung, RLS) and members of parliament like Helmut Scholz or Lothar Bisky.

He became the speaker of his caucus and chaired, in addition, the committee for Urban Development and Economics (Ausschuss für Stadtentwicklung, Wirtschaft, Arbeit, Verkehr und Umwelt).

[4] With assuming the office of Lord Mayor in Frankfurt (Oder), Wilke forfeits his membership in the Landtag.