[3] Lodi subsequently represented the under-23 in the Campeonato Paranaense, and scored his first senior goal on 25 March 2018, netting the opener in a 5–0 home routing of Maringá.

[9] On 16 May 2021, Lodi came on as a substitute and scored a late equalizing goal in the eventual 2–1 home win over Osasuna that would keep the club in the title race against Real Madrid.

[11] On 15 March 2022, Lodi scored his first Champions League goal to help Atlético Madrid beat Manchester United 1–0 at Old Trafford and qualify for the quarter-finals, securing a 2–1 aggregate win.

[14] On 14 July 2023, Olympique de Marseille confirmed that they had reached an agreement to acquire Renan Lodi from Atlético Madrid, having already agreed personal terms with him,[15] for a transfer fee of €13 million with a 20% sell-on clause.

[16] On 17 January 2024, Lodi signed a three-and-a-half-year contract with Saudi Pro League club Al Hilal for a reported fee of €23 million.