Train 100.015 set one of the most important speed records in Spain, reaching 356.8 kilometres per hour (221.7 mph) on a test run.

In 2007, after fifteen years of service—half of the trains' expected working life—the entire Class 100 fleet was refurbished.

In February 2011, on account of financial pressures, RENFE announced that, instead of buying 10 new trains to cover the Paris-Madrid route, it would convert AVE Class 100 trains for the route, at a cost of €30 million, rather than €270 million.

RENFE announced that the capacity would be increased to keep the cost down, in addition to the conversion work planned for the trains' electrification and signaling systems.

[2] Air Nostrum propose to lease some from RENFE to operate services from Madrid Atocha to Gare de Montpellier-Saint-Roch from October 2018.