Reseda Boulevard is a targeted Vision Zero corridor and is included in Mayor Eric Garcetti's Great Streets Initiative which calls for protected bicycle lanes, bus boarding islands, hybrid protected left turn signals and improved bus shelters.

[2] In 1977 the Los Angeles City Council failed to approve a plan to create a "Reseda to the Sea" link from the San Fernando Valley to L.A.'s Westside at Sunset Boulevard.

Although no alternative plans were evaluated, the city continued to maintain an easement of the proposed alignment until at least 1991.

This, along with an ongoing requirement that developers continue to dedicate and extend Reseda as far south as Mulholland Drive to improve fire safety, sparked criticism and protests by environmental and community activists.

Damage occurred throughout the San Fernando Valley, though areas of more widespread destruction followed the boulevard's northern course, including the Northridge Meadows Apartments, where sixteen people died when the top two floors collapsed on the ground-floor.