The function is thought to be mixing gastric contents with intestinal refluxate in order to buffer the former and give it momentum in preparation of vomiting.
During this time, the inspiratory (inhalatory) movements of the chest wall and diaphragm are opposed by the expiratory contractions of the abdominal musculature.
[5] Retching comprises a rhythmically alternating (about once per second) elevation and descension of the entire pharyngolaryngo-esophago-gastric apparatus in synchrony with the movement of the diaphragm.
[8] The treatments for significant retching include correction of fluid and electrolyte balance, nutritional support and medications like phenothiazines (such as Compazine and Phenergan), 5-HT3 antagonist (such as Zofran), dopamine receptor antagonists (such as Reglan), antihistamines (Antivert, Dramamine, Benadryl) and anticholinergics (scopolamine).
An implanted device with attached electrodes into the gastric wall can be an option for patients with refractory nausea and vomiting.