Reticular pigmented anomaly of the flexures (also known as dark dot disease and Dowling–Degos disease) is a fibrous anomaly of the flexures or bending parts of the axillae, neck and inframammary/sternal areas.
[2]: 856 It is an autosomal-dominant pigmentary disorder that may appear in adolescence or adulthood.
This condition is due to mutations in structural/desmosomal proteins found within stratified squamous epithelium.
[4] Ankyrin: Long QT syndrome 4
This cutaneous condition article is a stub.