Set some years after the events of the first movie, Captain Delano (Charles Napier) sends Sam Hell to infiltrate Frog Town again to rescue Texas Rocket Ranger John Jones (played by Lou Ferrigno) who crash landed.

In what may be a direct reference to his Incredible Hulk fame, Jones is an unwilling test subject who is modified and turned into a frog-person, giving him superhuman strength.

[2] The tests are conducted by Professor Tanzer (Brion James) and Nurse Cloris (Linda Singer).

Hell must journey to the Frogtown Mutant Reservation in a desperate attempt to stop the planned mutation.

Notable co-stars of the cast include: Don Stroud, Brion James, Charles Napier, Rhonda Shear.