[4] The Hitchcock House is located west of the city limits of Lewis, on a hill overlooking the western bank of the East Nishnabotna River.

It is a two-story structure, built out of locally sourced random ashlar sandstone, and resting on a rubblestone foundation.

Unusual features of its interior include an apparently purpose-built basement chamber, whose access was probably concealed by a false cabinet.

Hitchcock was involved in the American abolitionism movement known as the Underground Railroad, giving sanctuary to escaped slaves.

It underwent a major restoration in the 1980s, and is now managed by the county as a historic house museum, interpreting the history of the Hitchcock family and the Underground Railroad.