Rhinophyma is a condition causing development of a large, bulbous nose associated with granulomatous infiltration, commonly due to untreated rosacea.
[2] Rhinophyma can cause psychological distress due to its effect on one's personal appearance,[5][2] as well as social perception of a link with alcoholism.
[2] Rhinophyma develops in certain individuals with an unknown predisposition from long-standing rosacea which has progressed to a severe form.
[2] Rhinophyma is characterised by hypertrophy of nasal skin, with hyperplasia and fibrosis of the sebaceous glands and connective tissue.
[2] The exact pathophysiological mechanism underlying the development of rosacea and rhinophyma is unknown, but a combination of neurovascular and immune disturbance is thought to be involved, causing inflammation, fibrosis, and vascularisation.
[2] Treatment consists of paring down the bulk of the tissue with a sharp instrument or carbon dioxide laser and allowing the area to re-epithelialise.
[2] In the United States, people of predominantly Asian and African ancestry are only rarely affected by the condition.