It runs approximately 17 miles (27 km) from Route 14 in Foster to Broad Street in Cranston.

It roughly follows the shore of the Scituate Reservoir before passing over its dam.

It passes over I-295 without an interchange and heads towards downtown Cranston.

After passing the city center as a main east–west corridor, Route 2 passes Route 10's southern terminus.

It passes US 1A and ends at Broad Street, an old alignment of US 1A, 0.3 miles (0.48 km) later.