Adrian Lewis Morgan debuted as Jimmi Clay in September 2005 and has gone on to be the longest-serving cast member on Doctors.
[2] He joined the cast shortly after his role in Holby City had ended; he was a fan of the soap and was excited to audition for a regular part.
[3] Producers introduced the character's wife, Amanda (Emma Samms), shortly after his arrival, and he later established relationships with detective Eva Moore (Angela Lonsdale) and Cherry Malone (Sophie Abelson), the latter of whom he married.
[6] Amanda Vardalis (also Clay), portrayed by Emma Samms, initially appeared between 14 October and 9 December 2005, before returning for a brief stint from 27 April to 30 May 2018.
Amanda was introduced as the older wife of Jimmi Clay (Adrian Lewis Morgan) and is a complementary therapist.
Despite her success in American series following her exit, Samms "jumped at the chance" to return to Doctors since she enjoyed her initial stint on the soap, particularly working with Morgan.
Elizabeth was introduced to the Mill Health Centre as a doctor who had previously worked in poor parts of Asia.
Due to her experiences there, Elizabeth is often shown to be short and up-front with patients who she sees to be wasting NHS time.
Mac McGuire (Christopher Timothy) offers Elizabeth a chance to go into partnership with him at the Mill, but not wanting to stay around and cause more upset for Nick, she declines and leaves Letherbridge.
[10] For her role as Elizabeth, Griffiths received a nomination for Sexiest Female at the 2006 British Soap Awards.
It included misdiagnosing a patient who then died and being suspended by the General Medical Council and forced to retrain as a doctor.
[12] Nick is shown to be a very active person who is up for an adventure, with his hobbies including climbing mountains and playing rugby.
[10] For his role as Nick, McKell received nominations for Sexiest Male at the 2006, 2007 and 2008 British Soap Awards.
[17] Her profile explained that Donna is "a little too interested in the workings at the Mill Health Centre" and she was shown to be a fiery character in the soap, with scenes of her losing temper and getting official warnings from practice manager Julia Parsons (Diane Keen).
[18] For her role as Donna, Howe-Douglas received nominations for Best Comedy Performance and Best Newcomer at the 2007 British Soap Awards.
[20] These included her friendship with Ruth Pearce (Selina Chilton) becoming complicated by Ruth's bad mental health, learning that she has been in an incestuous relationship with her half-brother, her tumultuous relationship with mother Vera (Doña Croll) and leaving the Mill to work as a military nurse.
On his BBC Online profile, he was described as "absent-minded and a bit of a ditherer" but it noted Joe's skill for weighing things up and never losing focus.
[22] His teenage daughter, Emily Fenton (Rachael St. Rose/Florence Hoath), is introduced alongside him, and Joe's backstory involving his divorce from wife Annie is explored.
[22] Boxer announced in March 2008 that he had quit Doctors and finished filming two months prior to making his decision public.
Producer Peter Eryl Lloyd said that the team were "all extremely sad" by Boxer's departure from the soap due to his acting skills and the warmth that he brought to the role.
"[23] Joe's initial final scenes aired in late 2008, but he returns on a visit in 2010, where he hires Ruth Pearce (Selina Chilton).
[25] Will tells Steph Lynn (Tara Wells) about what he saw, but as Adrian is a clinical lead in the hospital, she tries to discourage Will from taking it higher.