Three structural classes of L13 ribosomal protein leaders were detected by different bioinformatics approaches: in B. subtilis and other low-GC Gram-positive bacteria.,[1] in E. coli [2][3] and in Bacteroidia.

[4] Although these RNAs are expected to perform the same biological function, they do not appear to be structurally related to one another.

The E. coli example has been experimentally confirmed, though the experiments are not comprehensive.

[3][2] The other two leader structures are thus far not based on experimental support.

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