His voice acting for video games includes playing The Mouth of Sauron in The Lord of the Rings: Gollum, Frank Fairburne in Strange Brigade, and various characters in the Total War: Warhammer series.
Between 2010 and 2015, Keeble appeared as various characters in sketches for Lee Nelson's Well Good Show, Alan Carr's Summertime Specstacular, Alan Carr's New Year Specstacular, hidden camera show Fool Britannia (starring Dom Joly), and had small roles in sitcoms Birds of a Feather and The Delivery Man.
In November 2016 he regularly appeared on the entertainment television series Animal Antics on Viasat Nature, directed by Nick Mavroidakis (Rude Tube).
[10] He provided the voice of the radio DJ on the Halloween special live episode of Inside No.9 broadcast on BBC Two on 28 October 2018.
[18] That year he also appeared as Tom Taylor the tree surgeon in Not Going Out, group leader Jared in Trying on Apple TV, and as a priest marrying Johnny Vegas and Sian Gibson's characters in Murder, They Hope.
In 2024 he appeared in Truelove opposite Phil Davis and Lindsay Duncan, Meet the Richardsons playing Jon Richardson's dentist, Kaos, Rivals playing TV director Brian Hetherington (reunited with Good Omens co-star David Tennant), and Christmas comedy film Bad Tidings with Lee Mack and Chris McCausland.