[4] He became a fan of stand-up comedy from watching television as a child and cites acts featured on The Ed Sullivan Show as a big influence.

[5] Vos began his stand-up career in 1984, choosing to pursue it full-time as he "failed at everything else",[2] and developed his act in local clubs.

[4] In 1995, Vos became the first white comic to perform a set on Def Comedy Jam on HBO, a show usually featuring African American comedians.

[7] In 2001, Vos played the bouncer and wrote and performed skits on the British television show The People vs. Jerry Sadowitz.

Vos was a frequent guest on the Opie and Anthony radio show,[8][4] with jokes centered at his expense, most often highlighting his speech impediment or lack of intellect.

When the show aired on SiriusXM Radio, Vos hosted a Saturday night program with his wife Bonnie McFarlane.

[12] After struggling with crack cocaine and alcohol addiction throughout his 20s, Vos completed a one-month rehabilitation course in 1987, three years into his comedy career.