Lui is currently a breaking news anchor for NBC and MSNBC, broadcasting from 30 Rockefeller Plaza in Midtown Manhattan, New York City.

[4] Lui is also a columnist, contributing to publications including USA Today, Politico, The Seattle Times, Detroit Free Press, and San Francisco Chronicle.

[5] Lui's enterprise reporting has focused on humanitarian issues including gender equality, human trafficking, and affordable housing.

[8] Lui has directed two Academy Award qualified films, Sky Blossom in 2020, and Unconditional in 2023, which was screened at the White House by First Lady Jill Biden.

[9][10] Lui started in business in 1985, working in manufacturing, strategy consulting, food and beverage, environmental, oil, and technology industries.

[12] After Mrs. Fields, Lui entered college, followed by work at Clean Environment Equipment (QED), where he led its global advertising and public relations.

[14] His patented payment infrastructure bypassed MasterCard and Visa, enabling consumers to pay for goods and services by connecting directly to their bank.

[16] As an ambassador for Plan International USA, Lui works to identify and advise on ways of talking about the role male adults and children have in gender inequality and female victim blaming, as well as help to generate organizational growth strategies.

[18][19] The U.S. Department of Justice asked Lui to present his work on trafficking at its annual gathering of attorneys and immigration officers in Atlanta in 2012.

[20][21] Lui has worked with the Aspen Institute for several years, speaking at its annual, C-SPAN broadcast symposium on the "State of Race in America".

[23] He is a UN Foundation Fellow and hosted programs alongside former Secretary of State Madeleine Albright[24] and UN Secretary-General Ban Ki-moon for the United Nations Association of New York.

After the election, Lui returned to college and planned to write on policy and the affairs of state, subscribing to The Washington Post when it had to be mailed to the West Coast.

[35][36] He also conducted Asian Pacific American Institute on Congressional Studies (APAICS) training sessions for elected and appointed officials.

Lui also contributes political opinion pieces to publications, including The Seattle Times,[37] San Francisco Chronicle,[38] Politico,[39] and Huffington Post.

[18] His field reporting explored political and civil rights controversies in the Asian-American community, including the 1882 Chinese Exclusion Act, which led to a system of illegal immigrants called paper sons.

[47] Some of the events he's anchored breaking coverage of include the Scotland independence vote, 2013 government shutdown, Boston Marathon bombing, Japanese earthquake and tsunami, NATO's attack in Libya, and the Arab Spring and Egypt’s revolution.

[33][49] In an NBC News investigation, Lui reported on a phenomenon involving high-volume brothels in the U.S. where women are forced to have sex up to a hundred times a day.