Tufton was the third son of John Tufton, 2nd Earl of Thanet and Lady Margaret, daughter of Richard Sackville, 3rd Earl of Dorset and Lady Anne Clifford.
[citation needed] He sat as Member of Parliament for Appleby from 1679 to 1680,[2] when he succeeded his elder brother John Tufton, 4th Earl of Thanet in the earldom and entered the House of Lords.
[citation needed] He also inherited the office of High Sheriff of Westmorland (1680–1684).
Lord Thanet died unmarried in March 1684 and was succeeded in his titles by his younger brother, Thomas.
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