Rincon Center is a complex of shops, restaurants, offices, and apartments in the South of Market neighborhood of Downtown San Francisco, California.

Rincon Center occupies an entire city block near the Embarcadero, bounded by Mission, Howard, Spear, and Steuart Streets.

Southern Pacific (SP) originally purchased the land where the original Rincon Annex was completed, next to its headquarters for the extension of its rail line to downtown San Francisco, but the western terminus of the San Francisco–Oakland Bay Bridge interfered with the proposed site and the increasing usage of the automobile also reduced demand for SP's Peninsula Commute service.

[1] At its peak, there were 1,000 to 1,500 Postal Service employees working simultaneously in the building; air conditioning was installed in 1958 to reduce interior temperatures.

[1] The United States Postal Service (USPS) was spun off as a government corporation in 1972 and because it was less efficient to sort mail in a multilevel facility,[1] the USPS began negotiations to move the mail sorting facility from Rincon Annex to India Basin Park in 1976;[4] the move was completed by 1979.

[1] The interior of the lobby (parallel to the Mission and Spear street facades) features the History of San Francisco mural series, comprising 27 tempera-on-gesso murals painted by the Russian immigrant artist Anton Refregier from 1941 to 1948 under the Section of Painting and Sculpture of the United States Department of the Treasury.

The San Francisco Board of Supervisors subsequently adopted the Rincon Point – South Beach Project Area Redevelopment Plan on January 5, 1981, which provided controls for land use, development standards, and urban design guidelines for the area including Rincon Annex.

[20] Until the COVID-19 pandemic, San Francisco City Guides led walking tours of the Rincon Annex murals.

San Francisco approved an amendment to the redevelopment plan to allow the ground floor retail space to be used as offices in December 2020.