The Rio Mayo titi is better adapted to moderately populated areas, thus overpopulation negatively impacts the species.

Neotropical Primate Conservation, Proyecto Mono Tocón and Amazónicos para la Amazonia are working in the more southern areas to protect the monkey.

[6] The Rio Mayo titi is a fairly inconspicuous creature, making observation and research difficult to obtain.

[8] Rio Mayo titis usually live in dry woodland areas with a lot of vines and plants.

They are found in Peru in the northern part of the Department of San Martin, at altitudes of 750–950 meters and also in the foothills of the Andes.

The family was observed to live in bamboo stands and low forests with trees with a mean height of 6.8 meters.

This species' ability to hunt insects so easily is especially important for survival in times of scarce food availability.

Before their death, samples of Atriotaenia megastoma were taken, dehydrated, and preserved in order to study their anatomy and reproductive organs.

Ultimately, the study showed that P. oenanthe is a new, definitive host for the parasite, and could be another factor in the species' decline.