As a young woman, wanting to become a dancer, she attended classical dance classes for five years in Genoa.

[1] In 1967, she was discovered by director Sergio Pastore, with whom she would make her debut in the film Omicidio a sangre freddo that same year.

This was the beginning of a career as an actress of about 16 years, during which she would appear in 33 films, especially in the police and horror genres.

Apart from most of the works, which were low-budget (including several by Renato Polselli, Luigi Batzella or Amasi Damiani), Calderoni was also hired by some of the most important directors of Italy at the time, such as Elio Petri, Ettore Scola and Eriprando Visconti.

Although she was never known by a wider audience, she was able to acquire cult status over the years.