La Roy appeared in over 50 films, the best known of which was Blonde Venus, which starred Marlene Dietrich.

[2] Her early years saw her work as both a dress designer and a stock company actress,[3] before moving onto vaudeville, where she became a dancer.

[4] In 1929, she made her film debut in The Delightful Rogue, starring opposite matinee idol Rod La Rocque.

[5] Over the next several years, working as part of the RKO Radio Pictures stable, she appeared in both starring and supporting roles.

[5] After retiring from film, for the most part, in the early 1940s, she ran the Rita La Roy Modeling School and Agency.