After flowing through Minera it turns south-east, past Coedpoeth, Bersham and Rhostyllen and through the Erddig Country Park, then east, passing slightly to the south of Wrexham.

Large waterwheels powered the bellows blasting air into the iron furnaces at Bersham, and drove winding and pumping machinery in the lead mines.

The population grew dramatically as the Industrial Revolution drew workers to the Wrexham area, serving the rapidly developing coal mines, lead mines, limestone quarries, ironworks and lead smelting works.

The fertile Clywedog flood plain had always provided rich pasture and corn; but, to meet the increased demand for food for the expanding work force, new corn mills were built and additional areas of woodland were cleared for growing crops.

When steam power took over in the late 19th and 20th centuries, new industries no longer needed to be sited close to the river.