The modern school houses a studio, workshop space and art shop in the building.

When built, it originally was set in its own grounds, surrounded by gardens and trees, however these were removed in the 20th century for the widening of roads following an increase in traffic in the area.

[4] The building has a stone portico on its front, which was a financed gift from Thomas Taylor Griffith, who has played a role in the infirmary's establishment and served as the hospital's physician.

The Wrexham Dispensary (later the Wrexham Infirmary) was founded in May 1833 on Yorke Street[6][5] by Watkin Williams Wynn, following the efforts of Thomas Taylor Griffith, a local physician who had attended Princess Victoria (later Queen Victoria) who had taken ill during a visit at Wynnstay.

[9][10] The building on Regent Street was built in 1838–39[1][11] as The Infirmary,[7][8] at the cost of £1,800 (equivalent to £204,712 in 2023), which was raised from charitable donations.

[4][7][8][12] In its first year, the infirmary received support from the public, and financial help from benefactors of local businesses.

[4][5] Although by 1918, it was decided the hospital would be moved to a new location to act as a memorial to those lost in World War I.

[8] Extensions of the building to the Regent Street and Bradley Road elevations appear to date to the early 20th century, possibly inline with its change of use.

[2] The building completed a refurbishment in February 2022, which started in 2021, as part of the university's Campus 2025 programme.

[12] In June 2018, the school held a summer show of work by its students open to the public.