Post-World War II, in 1954, the university relocated to its present campus in Loyola Heights, Quezon City, and eventually sold the Ermita site (now Robinsons Manila).

[12] By 1976, the Graduate School of Arts and Sciences had moved to Loyola Heights, and the Padre Faura campus was finally closed in 1977.

[13] In the 1970s, Ateneo students became active in protests against the Marcos dictatorship and its imposition of martial law,[14] and many later participated in the 1986 People Power Revolution.

[18] The university continued to expand and innovate, launching the Pathways to Higher Education initiative in 2002,[19] and consecrating the Church of the Gesù at the Loyola Heights campus in July 2002.

[21] The Manuel V. Pangilinan Center for Student Leadership opened in 2006, and the Ateneo School of Medicine and Public Health began operations in 2007.

[22] In recent years, significant events include a shooting incident in July 2022 that led to the cancellation of the law school's graduation ceremonies,[23] and the consolidation of the university's higher education units in October 2022.

[24] Ateneo de Manila's main campus is located in Loyola Heights, Quezon City,[25] covering 83 hectares (210 acres).

[26] In 2018, the university inaugurated the Areté, a creative hub that includes the Ateneo Art Gallery, theaters, and collaborative spaces.

[27] The Rizal Library and several research centers are located here, including the Institute of Philippine Culture and the Manila Observatory.

[41] The Ateneo de Manila Senior High School (ASHS) offers the eleventh and twelfth grades since 2013, and became co-educational in 2016.

[43] In May 2024, president Roberto Yap appointed Rosanna “Sansan” M. Borja as Senior High School Principal for a 3-year term (July 1, 2024-May 2027).

[49] Ateneo de Manila University emphasizes a liberal arts undergraduate core curriculum that includes philosophy, literature, theology, history, and the social sciences.

[57] The CoE status is given to Literature (English), Philosophy, Business Administration, Entrepreneurship, Biology, Chemistry, Information Technology, Mathematics, Physics, Psychology and Sociology.

[59] The school continues to consistently have the highest passing rate for first-time examinees, topping the 2020/2021 and 2022 Philippine Bar Examinations.

[64] Ateneo houses numerous research centers focusing on disaster risk reduction, public education, human migration, and governance, among other fields.

Key initiatives include the Ateneo-Mangyan Project for Understanding and Development, the Bigay Puso program, and house-building activities with Gawad Kalinga.

[65][66] The university's main social action program is its partnership with Gawad Kalinga, focusing on community-building and rehabilitation efforts in various regions.

The New Rizal Library, inaugurated in November 2009, contains the circulation section, technical services, and modern study areas.

[80][81] The Ateneo College Glee Club (ACGC) is the oldest university chorale in the Philippines and has achieved international recognition for its performances.