His West Point class of 2004 classmates include U.S. representatives John James, Pat Ryan, and Wesley Hunt.
Upon completing his military service, Mercuri enrolled in night classes offered by the University of Massachusetts Amherst and worked for two accounting firms in New York City.
With his wife, Kelsey, Mercuri owns a small business located in Wexford.
[2][3] After incumbent representative Mike Turzai of House District 28 announced that he would not run for reelection in 2020, Mercuri won a Republican Party primary against Michael Heckmann and Libby Blackburn, with Turzai's endorsement.
[6][7] On August 15, 2023, Mercuri declared his candidacy for the Republican nomination for Pennsylvania's 17th congressional district, currently held by Democrat Chris Deluzio.