[8] Morrow's film career began when he appeared as an extra at age 18 on Saturday Night Live.

[10] He later appeared in the Dentyne gum commercials where he would slyly utter the "Time to walk the dog" catch phrase.

[11][12] Morrow's character, Joel Fleischman, is "a New York City physician who is surprised to be assigned to the isolated and icy town of Cicely, Alaska".

[28][29][30] On March 8, 2010, it was announced that Morrow had signed on to star in Jerry Bruckheimer's new series, The Whole Truth, on ABC.

[32] Morrow starred as Henry Rearden in Atlas Shrugged: Part III, which was released September 12, 2014.

[33] In 2017, Morrow starred in the recurring role of reporter Abe Leonard in the first season of the ABC political drama Designated Survivor.

[35] As of November 2018, news was released that a revival of Northern Exposure was in the works at CBS and that Morrow would return as Joel Fleischman.