Born in Newcastle West in County Limerick, the son of Michael Ambrose and Eliza Quaide, he was educated at Wier's School and Queen's College, Cork.
He qualified as a surgeon and set up a practice in the East End of London.
He decided not to stand in January 1910, and instead became involved with the British Labour Party, for which he stood unsuccessfully in Whitechapel and St Georges at the 1918 general election.
[1] Ambrose wrote A Plea for Industrial Regeneration of Ireland, published in 1909.
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