[3] He made his major-league debut two days later, when he replaced Álex González at shortstop in the eighth inning of a 7–1 loss to the New York Mets at Dolphins Stadium.

[6] In an exchange of players out of minor league options, Andino was traded to the Baltimore Orioles for Hayden Penn on April 1, 2009.

He made a barehanded catch of a Justin Morneau pop fly in foul territory during the sixth inning of a 6–1 win over the Minnesota Twins at Target Field on August 24, 2011.

[8] During the last two weeks of the 2011 campaign, Andino had three clutch hits that helped prevent the Boston Red Sox from clinching the American League Wild Card.

The first was a two-out bases-clearing double down the right-field line off Jonathan Papelbon in the eighth inning of a 7–5 win at Fenway Park on September 20.

[9] Six nights later, on September 26, he became the first Oriole to achieve an inside-the-park home run at Camden Yards with a three-run shot off Josh Beckett in the sixth inning of a 6–3 triumph.

[11] Andino struck against Papelbon again with a two-out game-winning single to left field in the ninth inning of the regular-season-ending 4–3 victory at home on September 28.

[13] On September 7, 2012, Andino hit his career-high seventh home run of the season against New York Yankees pitcher Cody Eppley.