[1] He was a professor of molecular and cellular biology at Harvard University,[2] where he was the Richard L. Menschel Faculty Director of the Derek Bok Center for Teaching.

[9] After researching at Brandeis, Lue pursued graduate studies at Harvard University and obtained a Ph.D. in cellular biology in 1995.

His dissertation was titled "Molecular and biochemical characterization of Hdlg: the human homologue of the Drosophila discs-large tumor suppressor protein.

[2] He served as dean of Harvard Summer School and co-authored two textbooks on biology, researching science visualization.

[15] On March 1, 2013, Lue became the inaugural Richard L. Menschel Faculty Director of the Derek Bok Center for Teaching and Learning at Harvard University.