Saleh has also been assistant coach for the Houston Texans, Seattle Seahawks, Jacksonville Jaguars, and 49ers.

Born to Lebanese immigrants[1] in Dearborn, Michigan, Saleh is a 1997 graduate of Fordson High School[2][3] He attended Northern Michigan University in Marquette from 1997 to 2001,[4][5] where he earned a degree in finance and was a four-year starter for the Wildcats, earning all-conference honors as a tight end.

[12][13] In February 2011, Saleh was hired as the defensive quality control coach for the Seattle Seahawks under Pete Carroll.

On February 13, 2017, Saleh was named defensive coordinator for the San Francisco 49ers under new head coach Kyle Shanahan.

[18] Saleh helped lead the team to a 13–3 record and a Super Bowl LIV berth, where they lost to the Kansas City Chiefs, 31–20.

Saleh won his first game as a head coach three weeks later in a 27–24 overtime victory over the Tennessee Titans.

In his first season as head coach, the Jets finished 4–13,[22] missing the playoffs for the eleventh consecutive year.

[30] As part of an NFL heritage program,[31] he has occasionally worn a patch of the national flag of Lebanon sewn onto his sideline gear.