He played Ming, who transforms into a version of "Ming the Merciless", the arch-enemy of Flash Gordon, (during an hallucination that Sam J. Jones, the actor who plays Flash Gordon has) in Seth MacFarlane's film, Ted (2012).
He has also worked with MacFarlane on episodes of Family Guy, providing voices for several characters on the show.
In addition to Ted, Wu has appeared in the feature films Hot Tub Time Machine (as Mr. Wang), Juwan Chung's Baby (2008) (as the first Wah Ching gangster), Kung Phooey (as Lo Fat), and Phil Gorn's S.F.
Other TV shows he has appeared on include It's Always Sunny in Philadelphia (as the Man in the episode "The Gang Gets Trapped"), Good Luck Charlie (as Tim), Criminal Minds (as Paul Jones), The Defenders (as ADA Gow), Rubicon (as Chair Bumper Guy), The Good Guys (as Lee Huang), Bones (as James Sok), 7th Heaven (as Doctor Thomas Quawn), George Lopez (as Andrew), Threshold (as Philip Choi), Numb3rs (as Raymond Hmong), Clubhouse (as Von), Robbery Homicide Division (as Binh Joe/Bobby Poon), Boston Public (as Younger Man), Nash Bridges (as Consulate Guard) and the Chinese TV series Tou du.
Wu has also provided his voice talents to videogames such as Resident Evil 6, Ace Combat: Assault Horizon, MAG, L.A. Noire, Dead to Rights: Retribution, No More Heroes 2: Desperate Struggle, X-Men Origins: Wolverine (the voice of David Nord/Agent Zero), Metal Gear Solid 4: Guns of the Patriots,[1] GoldenEye: Rogue Agent, and Jet Li's Rise to Honor.