[1] After taking part in World War I as a volunteer, and participating in the Gabriele D'Annunzio-led occupation of Rijeka, in 1922 he graduated in architecture at the Sapienza University of Rome.
[1][2] In the 1920s he served as professor at the Classical Lyceum Umberto I in Naples, and collaborated with the Superintendency of Antiquities of Campania on several projects.
[1] Starting from 1924, he took part in several editions of the Venice Biennale, held several solo exhibitions, and cured several projects in Naples, including the Molosiglio Gardens, the restoration of the Madonna della Pace Church, and the African-Christianity pavilion at the 1940 Mostra d'Oltremare.
[1] Starting from the 1950s, Pane was a vocal opponent of the speculative construction and championed the inalterability of historic centres.
[1] He collaborated with various institutions including UNESCO,[1][3] and served as president of the interdisciplinary coordination committee for the reconstruction following the 1980 Irpinia earthquake.