Competing concurrently in MMA, Gracie is the 2016 ONE Light Heavyweight Champion, a former Strikeforce and UFC middleweight contender, holding at the time of his retirement in 2017 a professional record of 8–2.

[13] Competing at the 2003 ADCC Submission Fighting World Championship taking place for the first time in São Paulo on 17 May, Gracie arrived third in the -99 kilograms (218 lb) category, after defeating Mário Sperry and Rigan Machado but losing to John-Olav Einemo (2–0).

[15] At the 2004 World Jiu-Jitsu Championship, Gracie won the super heavyweight division but lost the final of the Absolute in a controversial match, after his opponent Ronaldo "Jacaré" Souza refused to tap out after getting armbared, got his arm dislocated as a result, then stayed away from Gracie with his broken left arm tucked into his belt, to keep his lead on points and win the match.

[16] In May 2005 Gracie competed in the ADCC Submission Wrestling World Championship taking place at the Walter Pyramid in Long Beach California.

[20] In April 2006 competing at the Pan American Championship taking place at California State University, Gracie won silver in the super heavyweight division after losing by points to Xande Ribeiro, the fourth loss of his career; he then won gold in Absolute after submitting the same Ribeiro in a triangle within 30 seconds.

[25] At the 2009 World Championship Gracie submitted all of his opponents, in the super heavyweight and in the absolute weight class, with a "cross choke from mount", winning double gold again.

[29] In July 2015, having not competed jiu-jitsu in 5 years, Gracie returned to competitive grappling to face Rodrigo Comprido, at a superfight American Nationals event during the UFC Fan Expo, winning via armbar in about 4 minutes.

[30] On 23 July 2017, at Gracie Pro jiu-jitsu an event taking place at Carioca Arena 1 in Rio de Janeiro, Gracie faced Marcus "Buchecha" Almeida for a 15-minute superfight dubbed "the most-anticipated rematch in jiu-jitsu history",[31] at that point both fighters held 10 world championship titles and were considered the greatest competitors in the sport.

[38] Gracie made his MMA debut in 2006, defeating veteran Ron Waterman by armbar submission in the 1st round at the Bodogfight pay-per-view USA vs Russia.

[40] Gracie made his middleweight debut against UFC veteran Keith Jardine at Strikeforce: Rockhold vs. Kennedy on July 14, 2012, winning the fight via unanimous decision.

Gracie returned to the Light Heavyweight division, known as "Cruiserweight" on ONE, and in his debut faced James McSweeney at ONE FC 23: Warrior's Way on December 5, 2014.

[52] Gracie returned to coach on season 7 of the Professional Grappling Federation on November 3 to 8, 2024, alongside Dean Lister, Pedro Sauer, and Carlos Machado.