Jackson also voiced the primate supervillain Mojo Jojo and the Rowdyruff Boy Butch on the Cartoon Network animated series The Powerpuff Girls.
His Mojo Jojo voice is later featured in The Powerpuff Girls Movie and Cartoon Network's FusionFall online video game.
He has contributed to Final Fantasy X and King's Quest VII and has done educational programs for both The Learning Company and Broderbund.
Jackson voiced Mr. Mucus in Mucinex ads for ten years, originating the rough New Yorker characterization in 2004.
Jackson reprised his voice role as Ghostface in the fifth Scream film, which was directed by Matt Bettinelli-Olpin and Tyler Gillett.