[1] In 2023, one of the hospitals nurse has been accused of switching patients' fentanyl IV with water in order to divert the supply to herself.

The East Wing was added in 1960 for $1.7 million, funded by the Hill–Burton Act, bringing the total number of beds to 160.

[6] In 2013, Asante Rogue Regional Medical Center was ranked as the top hospital in Oregon for Orthopedic Services, with special mention to the joint replacement program by Healthgrades.

[8] In August and September 2021, Asante made headlines when hundreds of their employees demonstrated to protest looming layoffs related to Governor Kate Brown's covid-19 vaccine mandate.

[12] The incident is believed to be tied to a handful of deaths and attorneys representing both living and deceased patients of have filed a $303 million lawsuit against the facility.